Aniline → HCID 22452199, compound

HRID 2185813Notes

Reaction equation

HRID 2185813 reaction equation
[CH:1]1([CH2:4][N:5]2[C:10](=[O:11])[C:9]([C:12](OCC)=[O:13])=[CH:8][C:7]([C:17]3[CH:22]=[CH:21][C:20]([O:23][CH3:24])=[CH:19][CH:18]=3)=[N:6]2)[CH2:3][CH2:2]1.[NH2:25][C:26]1[CH:31]=[CH:30][CH:29]=[CH:28][CH:27]=1>>[CH:1]1([CH2:4][N:5]2[C:10](=[O:11])[C:9]([C:12](=[O:13])[NH:25][C:26]3[CH:31]=[CH:30][CH:29]=[CH:28][CH:27]=3)=[CH:8][C:7]([C:17]3[CH:18]=[CH:19][C:20]([O:23][CH3:24])=[CH:21][CH:22]=3)=[N:6]2)[CH2:2][CH2:3]1

Participants

3

Reactant 2

HCID 6115AnilineHCID 22452200HCID 22452200, compound

Product 1

HCID 22452199HCID 22452199, compoundYield 12.2%

Procedure

2-Cyclopropylmethyl-4-ethoxycarbonyl-6-(4-methoxyphenyl)-2H-pyridazin-3-one and aniline were processed as in Example 70, whereby the title compound was obtained in a yield of 12.2%.

Sources & evidence

ORD record
ord-3965908ac6ce44dc85b730dafbcdfc70
Source dataset
uspto-grants-2002_06
Patent number
US06403586B1

Reaction notes

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