HuagongsheHuagongshe Chemistry Print Report · For research reference only
4,7,10,13,16,19-cis-Docosahexaenoic acid → N-(cis4,7,10,13,16,19-Docosahexaenoyl)-O-Phospho-2-Aminoethanol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4,7,10,13,16,19-cis-Docosahexaenoic acid | HCID 73013253 | — |
| Reactant | N-(cis-5,8,11,14-Eicosatetraenoyl)-O-Phospho-2-Aminoethanol | HCID 86583926 | — |
| Product | N-(cis4,7,10,13,16,19-Docosahexaenoyl)-O-Phospho-2-Aminoethanol | HCID 86583927 | — |
Reaction Steps
This compound was prepared as described above for (5), using 0.5 mmol (164 mg) of cis-4,7,10,13,16,19-docosahexaenoic acid; yield 99 mg (44%); Rf 0.10-0.15 (system B); 1H NMR (CD3SOCD3, 200 MHz) δ0.9-1.0 (t, 3H, ω-CH3); 2.0-2.1 (t, 2H, CH2CO); 2.2-2.4 (m, 4H, 2CH2CH═CH); 2.7-2.9 (br s, 10H, 5HC═CHCH2CH═CH); 3.4-3.5 (br s, 2H, CH2NH); 3.9-4.0 (br s, 2H, CH2OP); 5.2-5.4 (br s, 12H, 6HC═CH); 8.2-8.4 (m, 3H, NH and 2POH).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06403554B2 |
| Source dataset | uspto-grants-2002_06 |
| ORD ID | ord-09bb6663bc934f4e8094a4e631bd4549 |
| Source note | uspto-grants-2002_06 |