HCID 86758137, compound → HCID 10166762, compound

Participants

Reaction Steps

A mixture of N-(3-phenylsulfonyl-nipecotyl)-4-(2′,6′-dimethoxyphenyl)-2-benzyloxyphenylalanine (36 mg, 0.055 mmol) and 10% Pd/C (10 mg) were stirred vigorously under 1 atm of H2 until the starting material was consumed as judged by reverse phase HPLC analysis. The mixture was filtered through a pad of celite which was washed with MeOH and concentrated. The filtrate was triturated with Et2O to afford N-(3-phenylsulfonyl-nipecotyl)-4-(2′,6′-dimethoxyphenyl)-2-hydroxyphenylalanine as a solid.

Provenance & Evidence