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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 218604Generated: October 29, 2026

4-Benzyloxyindan-1-carboxylic acid → 4-benzyloxy-N-[(4-dimethylaminophenyl)methyl]-N-(4-isopropylphenyl)indan-1-carboxamide

https://huagongshe.com/reaction/218604

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Benzyloxyindan-1-carboxylic acidHCID 17854458—
ReactantN-(4-(Dimethylamino)benzyl)-4-isopropylbenzenamineHCID 21957887—
Product4-benzyloxy-N-[(4-dimethylaminophenyl)methyl]-N-(4-isopropylphenyl)indan-1-carboxamideHCID 59597231110.9%

Reaction Steps

By the reaction and treatment in the same manner as in Example 12 using 4-benzyloxyindan-1-carboxylic acid (0.7 g) and [(4-dimethylaminophenyl)methyl](4-isopropylphenyl)amine (0.7 g) as starting materials, 4-benzyloxy-N-[(4-dimethylaminophenyl)methyl]-N-(4-isopropylphenyl)indan-1-carboxamide (1.5 g) was obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08198454B2
Source datasetuspto-grants-2012_06
ORD IDord-0b7af73422ff4ec5b103aac78ca87860
Source noteuspto-grants-2012_06