HuagongsheHuagongshe Chemistry Print Report · For research reference only
7-Benzyloxy-1,2,3,4-tetrahydronaphthalene-1-carboxylic acid → 7-benzyloxy-N-[(1-ethylpyrazol-4-yl)methyl]-N-(4-isopropylphenyl)-1,2,3,4-tetrahydronaphthalene-1-carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 7-Benzyloxy-1,2,3,4-tetrahydronaphthalene-1-carboxylic acid | HCID 17854482 | — |
| Reactant | N-((1-Ethyl-1H-pyrazol-4-yl)methyl)-4-isopropylaniline | HCID 21957909 | — |
| Product | 7-benzyloxy-N-[(1-ethylpyrazol-4-yl)methyl]-N-(4-isopropylphenyl)-1,2,3,4-tetrahydronaphthalene-1-carboxamide | HCID 59597339 | 60.6% |
Reaction Steps
By the reaction and treatment in the same manner as in Example 4 using 7-benzyloxy-1,2,3,4-tetrahydronaphthalene-1-carboxylic acid (0.56 g) and [(1-ethylpyrazol-4-yl)methyl](4-isopropylphenyl)amine (0.49 g) as starting materials, 7-benzyloxy-N-[(1-ethylpyrazol-4-yl)methyl]-N-(4-isopropylphenyl)-1,2,3,4-tetrahydronaphthalene-1-carboxamide (0.61 g) was obtained. melting point: 100-101° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08198454B2 |
| Source dataset | uspto-grants-2012_06 |
| ORD ID | ord-b1f256b43a974124a62cb777e4322d3b |
| Source note | uspto-grants-2012_06 |