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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 218617Generated: October 30, 2026

4-Benzyloxyindan-1-carboxylic acid → 4-benzyloxy-N-[(1-ethylpyrazol-4-yl)methyl]-N-(4-isopropylphenyl)indan-1-carboxamide

https://huagongshe.com/reaction/218617

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Benzyloxyindan-1-carboxylic acidHCID 17854458—
ReactantN-((1-Ethyl-1H-pyrazol-4-yl)methyl)-4-isopropylanilineHCID 21957909—
Product4-benzyloxy-N-[(1-ethylpyrazol-4-yl)methyl]-N-(4-isopropylphenyl)indan-1-carboxamideHCID 5959728279.5%

Reaction Steps

By the reaction and treatment in the same manner as in Example 4 using 4-benzyloxyindan-1-carboxylic acid (0.54 g) and [(1-ethylpyrazol-4-yl)methyl](4-isopropylphenyl)amine (0.49 g) as starting materials, 4-benzyloxy-N-[(1-ethylpyrazol-4-yl)methyl]-N-(4-isopropylphenyl)indan-1-carboxamide (0.79 g) was obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08198454B2
Source datasetuspto-grants-2012_06
ORD IDord-7b1d185daac44913948c62cf1a61887f
Source noteuspto-grants-2012_06