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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 218622Generated: October 29, 2026

3,4-Dihydro-2H-1-benzopyran-4-carboxylic acid → N-[(1-ethylpyrazol-4-yl)methyl]-N-(4-isopropylphenyl)chroman-4-carboxamide

https://huagongshe.com/reaction/218622

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3,4-Dihydro-2H-1-benzopyran-4-carboxylic acidHCID 188669—
ReactantN-((1-Ethyl-1H-pyrazol-4-yl)methyl)-4-isopropylanilineHCID 21957909—
ProductN-[(1-ethylpyrazol-4-yl)methyl]-N-(4-isopropylphenyl)chroman-4-carboxamideHCID 5959737485%

Reaction Steps

By the reaction and treatment in the same manner as in Example 12 using chroman-4-carboxylic acid (0.27 g) and [(1-ethylpyrazol-4-yl)methyl](4-isopropylphenyl)amine (0.37 g) as starting materials, N-[(1-ethylpyrazol-4-yl)methyl]-N-(4-isopropylphenyl)chroman-4-carboxamide (0.52 g) was obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08198454B2
Source datasetuspto-grants-2012_06
ORD IDord-def460287ffd4be886272b9aa809adec
Source noteuspto-grants-2012_06