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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 218623Generated: October 25, 2026

6-Methoxychroman-4-carboxylic acid → N-[(1-ethylpyrazol-4-yl)methyl]-N-(4-isopropylphenyl)-6-methoxychroman-4-carboxamide

https://huagongshe.com/reaction/218623

Reaction equation

Participants

RoleNameHCIDCharge
Reactant6-Methoxychroman-4-carboxylic acidHCID 20273670—
ReactantN-((1-Ethyl-1H-pyrazol-4-yl)methyl)-4-isopropylanilineHCID 21957909—
ProductN-[(1-ethylpyrazol-4-yl)methyl]-N-(4-isopropylphenyl)-6-methoxychroman-4-carboxamideHCID 5959725260.4%

Reaction Steps

By the reaction and treatment in the same manner as in Example 12 using 6-methoxychroman-4-carboxylic acid (0.31 g) and [(1-ethylpyrazol-4-yl)methyl](4-isopropylphenyl)amine (0.37 g) as starting materials, N-[(1-ethylpyrazol-4-yl)methyl]-N-(4-isopropylphenyl)-6-methoxychroman-4-carboxamide (0.39 g) was obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08198454B2
Source datasetuspto-grants-2012_06
ORD IDord-a1937974ba6d40dca5c9f6d6cd5cf1b9
Source noteuspto-grants-2012_06