HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Benzyloxy-4-t-butyl-2-(1-octenyl)benzofuran → 4-Tert-butyl-5-hydroxy-2-octylbenzofuran
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Benzyloxy-4-t-butyl-2-(1-octenyl)benzofuran | HCID 54308722 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | 4-Tert-butyl-5-hydroxy-2-octylbenzofuran | HCID 23442864 | 70.4% |
Reaction Steps
Under hydrogen atmosphere, a solution of 1.1 g of 5-benzyloxy-4-t-butyl-2-(1-octenyl)benzofuran in 50 ml of acetic acid was stirred with 1.1 g of 10% palladium on carbon for 36 hours. After the palladium on carbon was filtered out, the filtrate was concentrated and the concentrate was purified by silica gel column chromatography (in chloroform) to give 0.6 g of 4-t-butyl-5-hydroxy-2-n-octylbenzofuran as a pale yellow oil (yield 69%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06403639B1 |
| Source dataset | uspto-grants-2002_06 |
| ORD ID | ord-ed523744bd7b41779a4d68e23dcc2d61 |
| Source note | uspto-grants-2002_06 |