HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Benzyloxy-1,2,3,4-tetrahydronaphthalene-1-carboxylic acid → 5-benzyloxy-N-(4-isopropylphenyl)-N-[(6-methoxypyridin-3-yl)methyl]-1,2,3,4-tetrahydronaphthalene-1-carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Benzyloxy-1,2,3,4-tetrahydronaphthalene-1-carboxylic acid | HCID 11208318 | — |
| Reactant | (4-Isopropylphenyl)[(2-methoxy-5-pyridyl)methyl]amine | HCID 21957879 | — |
| Product | 5-benzyloxy-N-(4-isopropylphenyl)-N-[(6-methoxypyridin-3-yl)methyl]-1,2,3,4-tetrahydronaphthalene-1-carboxamide | HCID 67184319 | 50.6% |
Reaction Steps
By the reaction and treatment in the same manner as in Example 12 using 5-benzyloxy-1,2,3,4-tetrahydronaphthalene-1-carboxylic acid (0.39 g) and (4-isopropylphenyl)[(6-methoxypyridin-3-yl)methyl]amine (0.35 g) as starting materials, 5-benzyloxy-N-(4-isopropylphenyl)-N-[(6-methoxypyridin-3-yl)methyl]-1,2,3,4-tetrahydronaphthalene-1-carboxamide (0.36 g) was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08198454B2 |
| Source dataset | uspto-grants-2012_06 |
| ORD ID | ord-31c47248c0214e1492a0cf2ab3c0b6ed |
| Source note | uspto-grants-2012_06 |