HuagongsheHuagongshe Chemistry Print Report · For research reference only
2h-1-Benzopyran-4-carboxylic acid,3,4-dihydro-8-(phenylmethoxy)- → 8-benzyloxy-N-(4-isopropylphenyl)-N-[(6-methoxypyridin-3-yl)methyl)chroman-4-carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2h-1-Benzopyran-4-carboxylic acid,3,4-dihydro-8-(phenylmethoxy)- | HCID 17854153 | — |
| Reactant | (4-Isopropylphenyl)[(2-methoxy-5-pyridyl)methyl]amine | HCID 21957879 | — |
| Product | 8-benzyloxy-N-(4-isopropylphenyl)-N-[(6-methoxypyridin-3-yl)methyl)chroman-4-carboxamide | HCID 59191185 | 70.6% |
Reaction Steps
By the reaction and treatment in the same manner as in Example 12 using 8-(benzyloxy)chroman-4-carboxylic acid (0.47 g) and (4-isopropylphenyl)[(6-methoxypyridin-3-yl)methyl]amine 0.43 g) as starting materials, 8-benzyloxy-N-(4-isopropylphenyl)-N-[(6-methoxypyridin-3-yl)methyl]chroman-4-carboxamide (0.61 g) was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08198454B2 |
| Source dataset | uspto-grants-2012_06 |
| ORD ID | ord-65eef4d805d14fceb5eff423ea80adc9 |
| Source note | uspto-grants-2012_06 |