HuagongsheHuagongshe Chemistry Print Report · For research reference only
Azetidine → 2-(Azetidin-1-yl)7-bromo-4-methoxybenzooxazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Azetidine | HCID 10422 | — |
| Reactant | 7-Bromo-4-methoxy-2-methylsulfanylbenzooxazole | HCID 22456651 | — |
| Product | 2-(Azetidin-1-yl)7-bromo-4-methoxybenzooxazole | HCID 22456655 | 59.5% |
Reaction Steps
Starting from 7-bromo-4-methoxy-2-methylsulfanylbenzooxazole (4.8 g) and azetidine (1.0 g). Purification by chromatography on silica eluting with 50% ethyl acetate in heptane afforded the title compound as a pink solid (2.95 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06403791B1 |
| Source dataset | uspto-grants-2002_06 |
| ORD ID | ord-e0f7a3c9d3d94720bae8ae7923006e2e |
| Source note | uspto-grants-2002_06 |