HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Difluoromethoxy-2-ethylbenzooxazole-7-carboxylic acid → HCID 10109411, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Difluoromethoxy-2-ethylbenzooxazole-7-carboxylic acid | HCID 22456643 | — |
| Reactant | 3-Ethyl-5-methylisoxazol-4-amine | HCID 22456668 | — |
| Solvent | Diethylether hexane | HCID 21584099 | — |
| Product | HCID 10109411 | HCID 10109411 | 54.6% |
Reaction Steps
Starting from 4-difluoromethoxy-2-ethylbenzooxazole-7-carboxylic acid (0.20 g) and 3-ethyl-5-methylisoxazol-4-ylamine (0.20 g). Purification by column chromatography on silica eluting 20-50% ethyl acetate in heptane afforded, after trituration with diethyl ether-hexane, the title compound as a white solid (0.155 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06403791B1 |
| Source dataset | uspto-grants-2002_06 |
| ORD ID | ord-6189d3cd665344b5bd13e8a26fa74005 |
| Source note | uspto-grants-2002_06 |