HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Amino-1-methyl-1H-pyrazole-4-carbonitrile → HCID 10134851, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Amino-1-methyl-1H-pyrazole-4-carbonitrile | HCID 219740 | — |
| Reactant | HCID 69840901 | HCID 69840901 | — |
| Product | HCID 10134851 | HCID 10134851 | 72.7% |
Reaction Steps
Starting from 2-(azetidin-1-yl)-4-difluoromethoxybenzooxazole-7-carboxylic acid 4-nitro-phenyl ester (178 mg) and 5-amino-1-methyl-1H-pyrazole-4-carbonitrile (107 mg). Purification by column chromatography on silica eluting with 3% methanol in dichloromethane followed by trituration in diethyl ether afforded the title compound as a white solid (124 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06403791B1 |
| Source dataset | uspto-grants-2002_06 |
| ORD ID | ord-dfcdd4e727684d0c967a42f9c87eb9c7 |
| Source note | uspto-grants-2002_06 |