Trifluoroacetic acid → HCID 14619285, compound

Participants

Reaction Steps

To a solution of (S)-(+)-N-Boc-2-phenethylpyrrolidine (0.53 g, 1.93 mmol) in 5 mL of CH2Cl2 at 0° C. was added 5 mL of TFA. The solution was warmed to room temperature and stirred for 3 hours. The organic layer was concentrated under reduced pressure and redissolved in CH2Cl2. The organic layer was washed with 1 M NaOH, dried over Na2SO4, filtered and concentrated under reduced pressure to give the title compound as a light yellow oil (0.31 g, 91%). ES (+) MS m/e=176 (M+H).

Provenance & Evidence