tert-Butyl acetate → HCID 21348825, compound

HRID 2186532Notes

Reaction equation

HRID 2186532 reaction equation
[C:1]([O:4][C:5]([CH3:8])([CH3:7])[CH3:6])(=[O:3])[CH3:2].[CH:9]12[CH:18]3[CH2:19][CH:15]([CH:16]=[CH:17]3)[CH:14]1[CH:13]1[CH2:20][CH:10]2[CH:11]([CH:21]=[O:22])[CH2:12]1>>[OH:22][CH:21]([CH:11]1[CH2:12][CH:13]2[CH2:20][CH:10]1[CH:9]1[CH:14]2[CH:15]2[CH2:19][CH:18]1[CH:17]=[CH:16]2)[CH2:2][C:1]([O:4][C:5]([CH3:8])([CH3:7])[CH3:6])=[O:3]

Participants

3

Reactant 2

HCID 10908tert-Butyl acetateHCID 20243476HCID 20243476, compound

Product 1

HCID 21348825HCID 21348825, compoundYield 93%

Procedure

The procedure of Synthesis Example 1 was repeated except that tert-butyl acetate was used instead of 1-ethylcyclopentyl acetate, and 8-tetracyclo[4.4.0.12,5.17,10]-dodecene-3-carbaldehyde was used instead of 5-norbornene-2-carbaldehyde. There was obtained tert-butyl 3-hydroxy-3-(8-tetracyclo[4.4.0.12,5.17,10]dodecen-3-yl)propionate. Yield 93%.

Workup

  1. customThe procedure of Synthesis Example 1

Sources & evidence

ORD record
ord-59f232f5c67a458c8f8416b1e2bcdd73
Source dataset
uspto-grants-2002_06
Patent number
US06403822B2

Reaction notes

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