Cyclohexanol, 1-ethyl-, 1-acetate → HCID 21348840, compound

HRID 2186533Notes

Reaction equation

HRID 2186533 reaction equation
[C:1]([O:4][C:5]1([CH2:11][CH3:12])[CH2:10][CH2:9][CH2:8][CH2:7][CH2:6]1)(=[O:3])[CH3:2].[CH:13]12[CH2:19][CH:16]([CH:17]=[CH:18]1)[CH2:15][CH:14]2[CH2:20][C:21](=[O:23])[CH3:22]>>[OH:23][C:21]([CH3:22])([CH2:20][CH:14]1[CH2:15][CH:16]2[CH2:19][CH:13]1[CH:18]=[CH:17]2)[CH2:2][C:1]([O:4][C:5]1([CH2:11][CH3:12])[CH2:10][CH2:9][CH2:8][CH2:7][CH2:6]1)=[O:3]

Participants

3

Reactant 2

HCID 77346Cyclohexanol, 1-ethyl-, 1-acetateHCID 4585785HCID 4585785, compound

Product 1

HCID 21348840HCID 21348840, compoundYield 92%

Procedure

The procedure of Synthesis Example 1 was repeated except that 1-ethylcyclohexyl acetate was used instead of 1-ethylcyclopentyl acetate, and 3-(5-norbornen-2-yl)acetone was used instead of 5-norbornene-2-carbaldehyde. There was obtained 1-ethylcyclohexyl 3-hydroxy-3-methyl-4-(5-norbornen-2-yl)butyrate. Yield 92%.

Workup

  1. customThe procedure of Synthesis Example 1

Sources & evidence

ORD record
ord-98feb091a35b49f882daf67aa39f3513
Source dataset
uspto-grants-2002_06
Patent number
US06403822B2

Reaction notes

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