Sulfuric Acid → 3-Hydroxy-2-naphthoic acid

Participants

Reaction Conditions

Reaction Steps

To a 1 L autoclave, 800 g of aqueous solution containing 100 g of sodium 2-hydroxynaphthalene-3-carboxylate prepared by means of the Kolbe-Schmitt method was fed and heated to 160° C. An aqueous sulfuric acid solution (72%) was added dropwise to the solution over 50 minutes to adjust the pH of the mixture to 3.5. Then, the mixture was cooled to 80° C. at the rate of 0.4° C./min. At the same temperature, the mixture was filtrated to give 80.6 g of crystalline 2-hydroxynaphthalene-3-carboxylic acid.

Provenance & Evidence