2h-1-Benzopyran-4-carboxylic acid,3,4-dihydro-8-(phenylmethoxy)- → 8-benzyloxy-N-[(4-dimethylaminophenyl)methyl]-N-(4-isopropylphenyl)chroman-4-carboxamide

Participants

Role	Name	HCID	Charge
Reactant	2h-1-Benzopyran-4-carboxylic acid,3,4-dihydro-8-(phenylmethoxy)-	HCID 17854153	—
Reactant	N-(4-(Dimethylamino)benzyl)-4-isopropylbenzenamine	HCID 21957887	—
Product	8-benzyloxy-N-[(4-dimethylaminophenyl)methyl]-N-(4-isopropylphenyl)chroman-4-carboxamide	HCID 67183303	98.5%

Reaction Steps

By the reaction and treatment in the same manner as in Example 12 using 8-benzyloxychroman-4-carboxylic acid (0.54 g) and [(4-dimethylaminophenyl)methyl](4-isopropylphenyl)amine (0.51 g) as starting materials, 8-benzyloxy-N-[(4-dimethylaminophenyl)methyl]-N-(4-isopropylphenyl)chroman-4-carboxamide (1 g) was obtained.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US08198454B2
Source dataset	uspto-grants-2012_06
ORD ID	ord-b904fb2dffda470cafb02ab760641dbf
Source note	uspto-grants-2012_06