HuagongsheHuagongshe Chemistry Print Report · For research reference only
2h-1-Benzopyran-4-carboxylic acid,3,4-dihydro-7-(phenylmethoxy)- → 7-benzyloxy-N-[(4-dimethylaminophenyl)methyl]-N-(4-isopropylphenyl)chroman-4-carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2h-1-Benzopyran-4-carboxylic acid,3,4-dihydro-7-(phenylmethoxy)- | HCID 20273681 | — |
| Reactant | N-(4-(Dimethylamino)benzyl)-4-isopropylbenzenamine | HCID 21957887 | — |
| Product | 7-benzyloxy-N-[(4-dimethylaminophenyl)methyl]-N-(4-isopropylphenyl)chroman-4-carboxamide | HCID 59597376 | 106.3% |
Reaction Steps
By the reaction and treatment in the same manner as in Example 12 using 7-benzyloxychroman-4-carboxylic acid (0.6 g) and [(4-dimethylaminophenyl)methyl](4-isopropylphenyl)amine (0.57 g) as starting materials, 7-benzyloxy-N-[(4-dimethylaminophenyl)methyl]-N-(4-isopropylphenyl)chroman-4-carboxamide (1.2 g) was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08198454B2 |
| Source dataset | uspto-grants-2012_06 |
| ORD ID | ord-0129ee73cd554ec88a9c91c4f6ee0a0b |
| Source note | uspto-grants-2012_06 |