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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 218663Generated: October 30, 2026

2h-1-Benzopyran-4-carboxylic acid,3,4-dihydro-7-(phenylmethoxy)- → 7-benzyloxy-N-[(4-dimethylaminophenyl)methyl]-N-(4-isopropylphenyl)chroman-4-carboxamide

https://huagongshe.com/reaction/218663

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2h-1-Benzopyran-4-carboxylic acid,3,4-dihydro-7-(phenylmethoxy)-HCID 20273681—
ReactantN-(4-(Dimethylamino)benzyl)-4-isopropylbenzenamineHCID 21957887—
Product7-benzyloxy-N-[(4-dimethylaminophenyl)methyl]-N-(4-isopropylphenyl)chroman-4-carboxamideHCID 59597376106.3%

Reaction Steps

By the reaction and treatment in the same manner as in Example 12 using 7-benzyloxychroman-4-carboxylic acid (0.6 g) and [(4-dimethylaminophenyl)methyl](4-isopropylphenyl)amine (0.57 g) as starting materials, 7-benzyloxy-N-[(4-dimethylaminophenyl)methyl]-N-(4-isopropylphenyl)chroman-4-carboxamide (1.2 g) was obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08198454B2
Source datasetuspto-grants-2012_06
ORD IDord-0129ee73cd554ec88a9c91c4f6ee0a0b
Source noteuspto-grants-2012_06