Sodium borohydride → mycotrienol I

Participants

Reaction Steps

Mycotrienin II (1.00 g, 1.56 mmol) was reduced with NaBH4 as described by the literature method to afford 1.04 g of a crude material. The crude material was immediately oxidized with FeCl3 as described by the literature method to afford 600 mg of Mycotrienol I as a yellow solid after chromatography (25:1 CH2Cl2/methanol, Rf=0.44) in 87% combined yield.

Provenance & Evidence