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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 218668Generated: October 25, 2026

4-[(4-Bromoanilino)methyl]-N,N-dimethylaniline → N-(4-bromophenyl)-N-[(4-dimethylaminophenyl)methyl]-7-fluoro-1,2,3,4-tetrahydronaphthalene-1-carboxamide

https://huagongshe.com/reaction/218668

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-[(4-Bromoanilino)methyl]-N,N-dimethylanilineHCID 15174101—
Reactant7-Fluoro-1,2,3,4-tetrahydronaphthalene-1-carboxylic acidHCID 17854522—
ProductN-(4-bromophenyl)-N-[(4-dimethylaminophenyl)methyl]-7-fluoro-1,2,3,4-tetrahydronaphthalene-1-carboxamideHCID 1667966425.8%

Reaction Steps

By the reaction and treatment in the same manner as in Example 12 using 7-fluoro-1,2,3,4-tetrahydronaphthalene-1-carboxylic acid (0.41 g) and (4-bromophenyl)[(4-dimethylaminophenyl)methyl]amine (0.64 g) as starting materials, N-(4-bromophenyl)-N-[(4-dimethylaminophenyl)methyl]-7-fluoro-1,2,3,4-tetrahydronaphthalene-1-carboxamide (0.26 g) was obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08198454B2
Source datasetuspto-grants-2012_06
ORD IDord-06128b0c93c44b46a8c1116c6fed3742
Source noteuspto-grants-2012_06