1,2-Dichloroethane → HCID 7944366, compound

Participants

Reaction Steps

A solution of 4-diphenylacetylamino-benzoic acid (150 mg, 0.45 mmol), dimethylamine (2.0 M in THF, 203 mg, 0.24 mL, 4.5 mmol), EDC (86 mg, 0.45 mmol) and HOBT (61 mg, 0.45 mmol) in CH2Cl2 (15 mL) was stirred at room temperature for 17 h. The reaction mixture was diluted with CHCl3 and washed with 10 N HCl (4 mL), sat'd aq NaHCO3 (4 mL) and sat'd aq brine. The organic solution was dried and concentrated in vacuo to give the title compound as a white solid (100 mg).

Provenance & Evidence