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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 218680Generated: October 30, 2026

1,2,3,4-Tetrahydro-1-naphthoic acid → N-(4-butylphenyl)-N-[(4-dimethylaminophenyl)methyl]-1,2,3,4-tetrahydronaphthalene-1-carboxamide

https://huagongshe.com/reaction/218680

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,2,3,4-Tetrahydro-1-naphthoic acidHCID 12598146—
Reactant(4-Butylphenyl)[(4-dimethylaminophenyl)methyl]amineHCID 21957943—
ProductN-(4-butylphenyl)-N-[(4-dimethylaminophenyl)methyl]-1,2,3,4-tetrahydronaphthalene-1-carboxamideHCID 1027502596.1%

Reaction Steps

By the reaction and treatment in the same manner as in Example 12 using 1,2,3,4-tetrahydronaphthalene-1-carboxylic acid (0.70 g) and (4-butylphenyl)[(4-dimethylaminophenyl)methyl]amine (0.54 g) as starting materials, N-(4-butylphenyl)-N-[(4-dimethylaminophenyl)methyl]-1,2,3,4-tetrahydronaphthalene-1-carboxamide (0.81 g) was obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08198454B2
Source datasetuspto-grants-2012_06
ORD IDord-3585b10f6c3a4dbd89dd2d129448ea0b
Source noteuspto-grants-2012_06