HCID 22449944, compound → HCID 70178280, compound

Participants

Reaction Steps

A solution of 5 g (+) threo 1-(p-nitro-phenyl)-2-(4-benzylpiperidin-1-yl)-3-dimethylaminopropan-1-ol and 0.5 g of Pd/C 10% in 50 ml of ethanol was hydrogenated at normal pressure at 50° C. After removal of the catalist, the solution was concentrated to small volume affording 3.1 g of (+) threo 1-(p-amino-phenyl)-2-(4-benzylpiperidin-1-yl) -3-dimethylaminopropan-1-ol, m.p. 121-125° C.

Provenance & Evidence