1-Acetylamino-6,7,8,9-tetrahydro-5H-benzocycloheptene → 1-Acetylamino-6,7,8,9-tetrahydro-5H-benzocycloheptene-9-one
Reaction equation
[C:1]([NH:4][C:5]1[C:10]2[CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][C:9]=2[CH:8]=[CH:7][CH:6]=1)(=[O:3])[CH3:2].C(NC1C2C(=CC=CC=2)CCC1)(=[O:18])C>>[C:1]([NH:4][C:5]1[C:10]2[C:11](=[O:18])[CH2:12][CH2:13][CH2:14][CH2:15][C:9]=2[CH:8]=[CH:7][CH:6]=1)(=[O:3])[CH3:2]Participants
3
Procedure
The reaction was carried out in the same manner as in -Example 1-(1), except that 200 mg of the compound prepared in (1) above was used instead of 1-acetylaminotetraline of Example 1-(1). The reaction product was post-treated to produce 55 mg of the title compound.
Workup
- additionThe reaction product was post-treated
Sources & evidence
- ORD record
- ord-4d80aa3434c1462bac939af39c0d8e65
- Source dataset
- uspto-grants-2002_06
- Patent number
- US06407115B1
Reaction notes
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