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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 218686Generated: October 29, 2026

5-Benzyloxy-1,2,3,4-tetrahydronaphthalene-1-carboxylic acid → HCID 67183233, compound

https://huagongshe.com/reaction/218686

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-Benzyloxy-1,2,3,4-tetrahydronaphthalene-1-carboxylic acidHCID 11208318—
ReactantHCID 21957968HCID 21957968—
ProductHCID 67183233HCID 6718323370.8%

Reaction Steps

By the reaction and treatment in the same manner as in Example 12 using 5-benzyloxy-1,2,3,4-tetrahydronaphthalene-1-carboxylic acid (0.63 g) and (4-ethylphenyl)[(4-morpholinophenyl)methyl]amine (0.56 g) as starting materials, 5-benzyloxy-N-(4-ethylphenyl)-N-[(4-morpholinophenyl)methyl]-1,2,3,4-tetrahydronaphthalene-1-carboxamide (0.75 g) was obtained. By the reaction and treatment in the same manner as in Example 17 using this compound, N-(4-ethylphenyl)-5-hydroxy-N-[(4-morpholinophenyl)methyl]-1,2,3,4-tetrahydronaphthalene-1-carboxamide (0.51 g) was obtained. melting point: 200° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08198454B2
Source datasetuspto-grants-2012_06
ORD IDord-448f5a02027e4eefb474a4c82f3e4397
Source noteuspto-grants-2012_06