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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 218689Generated: October 30, 2026

5-Benzyloxy-1,2,3,4-tetrahydronaphthalene-1-carboxylic acid → HCID 67184160, compound

https://huagongshe.com/reaction/218689

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-Benzyloxy-1,2,3,4-tetrahydronaphthalene-1-carboxylic acidHCID 11208318—
ReactantHCID 68418942HCID 68418942—
ProductHCID 67184160HCID 6718416065.8%

Reaction Steps

By the reaction and treatment in the same manner as in Example 12 using 5-benzyloxy-1,2,3,4-tetrahydronaphthalene-1-carboxylic acid (1.94 g) and [(3,4-dibenzyloxyphenyl)methyl](4-isopropylphenyl)amine (2.5 g) as starting materials, 5-benzyloxy-N-[(3,4-dibenzyloxyphenyl)methyl]-N-(4-isopropylphenyl)-1,2,3,4-tetrahydronaphthalene-1-carboxamide (2.64 g) was obtained. By the reaction and treatment in the same manner as in Example 17 using this compound, N-[(3,4-dihydroxyphenyl)methyl]-5-hydroxy-N-(4-isopropylphenyl)-1,2,3,4-tetrahydronaphthalene-1-carboxamide (1.35 g) was obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08198454B2
Source datasetuspto-grants-2012_06
ORD IDord-35bef6f160504535b630b1d8b4d21e7e
Source noteuspto-grants-2012_06