HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Benzyloxy-1,2,3,4-tetrahydronaphthalene-1-carboxylic acid → HCID 67183270, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Benzyloxy-1,2,3,4-tetrahydronaphthalene-1-carboxylic acid | HCID 11208318 | — |
| Reactant | HCID 67183306 | HCID 67183306 | — |
| Product | HCID 67183270 | HCID 67183270 | 71% |
Reaction Steps
By the reaction and treatment in the same manner as in Example 12 using 5-benzyloxy-1,2,3,4-tetrahydronaphthalene-1-carboxylic acid (0.59 g) and [(4-benzyloxyphenyl)methyl](4-isopropylphenyl)amine (0.58 g) as starting materials, 5-benzyloxy-N-[(4-benzyloxyphenyl)methyl]-N-(4-isopropylphenyl)-1,2,3,4-tetrahydronaphthalene-1-carboxamide (0.74 g) was obtained. By the reaction and treatment in the same manner as in Example 17 using this compound, 5-hydroxy-N-[(4-hydroxyphenyl)methyl]-N-(4-isopropylphenyl)-1,2,3,4-tetrahydronaphthalene-1-carboxamide (0.33 g) was obtained. melting point: 241-243° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08198454B2 |
| Source dataset | uspto-grants-2012_06 |
| ORD ID | ord-b5ca78a1cbcb497fa20e5d03fcdbfed0 |
| Source note | uspto-grants-2012_06 |