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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 218705Generated: October 29, 2026

N,N-Dimethylaminoethyl chloride hydrochloride → HCID 59597273, compound

https://huagongshe.com/reaction/218705

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN,N-Dimethylaminoethyl chloride hydrochlorideHCID 11636816—
ReactantHCID 59597373HCID 59597373—
ProductHCID 59597273HCID 5959727338.7%

Reaction Steps

By the reaction and treatment in the same manner as in Example 106 using N-[(1-ethylpyrazol-4-yl)methyl]-6-hydroxy-N-(4-isopropylphenyl)-1,2,3,4-tetrahydronaphthalene-1-carboxamide (0.42 g) and 2-chloro-N,N-dimethylethylamine hydrochloride (0.22 g) as starting materials, 6-[2-(dimethylamino)ethoxy]-N-[(1-ethylpyrazol-4-yl)methyl]-N-(4-isopropylphenyl)-1,2,3,4-tetrahydronaphthalene-1-carboxamide (0.19 g) was obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08198454B2
Source datasetuspto-grants-2012_06
ORD IDord-4b06d393519a4993b3174adbdc8a5262
Source noteuspto-grants-2012_06