Isatoic Anhydride → HCID 22449860, compound

HRID 2187055Notes

Reaction equation

HRID 2187055 reaction equation
[NH2:1][CH2:2][CH2:3][CH2:4][N:5]1[CH2:10][CH2:9][CH:8]([O:11][CH:12]([C:19]2[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=2)[C:13]2[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=2)[CH2:7][CH2:6]1.[C:25]12[C:31](=[CH:32][CH:33]=[CH:34][CH:35]=1)[NH:30]C(=O)O[C:26]2=[O:27]>>[NH2:30][C:31]1[CH:32]=[CH:33][CH:34]=[CH:35][C:25]=1[C:26]([NH:1][CH2:2][CH2:3][CH2:4][N:5]1[CH2:6][CH2:7][CH:8]([O:11][CH:12]([C:19]2[CH:20]=[CH:21][CH:22]=[CH:23][CH:24]=2)[C:13]2[CH:14]=[CH:15][CH:16]=[CH:17][CH:18]=2)[CH2:9][CH2:10]1)=[O:27]

Participants

3

Reactant 2

HCID 8359Isatoic AnhydrideHCID 109693934-(Diphenylmethoxy)-1-piperidinepropaneamine

Product 1

HCID 22449860HCID 22449860, compoundYield 66%

Procedure

Using the method similar to that in Reference Example 1 and using 1-(3-aminopropyl)-4-diphenylmethoxypiperidine instead of 4-methoxybenzylamine and starting from isatoic anhydride (2.87 g), the title compound (6.19 g, 66%) was synthesized. This product was used in the next reaction without further purification.

Workup

  1. customThis product was used in the next reaction without further purification

Sources & evidence

ORD record
ord-6465d4ca851d4df78decdff7148ca4a3
Source dataset
uspto-grants-2002_06
Patent number
US06407116B1

Reaction notes

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