HRID2187101

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：O=S(=O)(CCN1CC[C@H](Cc2ccccc2)[C@H](O)C1)c1ccc(O)cc1

HCID9885963

未命名化合物

HCID11425445

未命名化合物

PRODUCTS

生成物

结构：CC(C)(C)OC(=O)NCCC(=O)NCCC(=O)Oc1ccc(S(=O)(=O)CCN2CC[C@H](Cc3ccccc3)[C@H](O)C2)cc1

HCID86584797

未命名化合物

收率 13%

PROCEDURE

实验过程

The title compound was prepared from (3S,4S)-4-[2-(4-benzyl-3-hydroxy-piperidin-1-yl)-ethanesulfonyl]-phenol and 3-(3-tert-butoxycarbonylamino-propionylamino)-propionic acid in 13% yield as a colorless solid.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-5a023a0de068482cba9bd6f11fe10939
来源数据集: uspto-grants-2002_06
DOI: 10.6084/m9.figshare.5104873.v1
专利: US06407235B1
来源说明: uspto-grants-2002_06

反应 SMILES

[CH2:1]([C@H:8]1[CH2:13][CH2:12][N:11]([CH2:14][CH2:15][S:16]([C:19]2[CH:24]=[CH:23][C:22]([OH:25])=[CH:21][CH:20]=2)(=[O:18])=[O:17])[CH2:10][C@H:9]1[OH:26])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[C:27]([O:31][C:32]([NH:34][CH2:35][CH2:36][C:37]([NH:39][CH2:40][CH2:41][C:42](O)=[O:43])=[O:38])=[O:33])([CH3:30])([CH3:29])[CH3:28]>>[CH2:1]([C@H:8]1[CH2:13][CH2:12][N:11]([CH2:14][CH2:15][S:16]([C:19]2[CH:24]=[CH:23][C:22]([O:25][C:42](=[O:43])[CH2:41][CH2:40][NH:39][C:37](=[O:38])[CH2:36][CH2:35][NH:34][C:32]([O:31][C:27]([CH3:28])([CH3:29])[CH3:30])=[O:33])=[CH:21][CH:20]=2)(=[O:18])=[O:17])[CH2:10][C@H:9]1[OH:26])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1