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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2187103Generated: October 26, 2026

(3S,4S)-4-[2-(4-benzyl-3-hydroxy-piperidin-1-yl)-ethanesulfonyl]-phenol → 4-[(tert-Butoxycarbonyl-methyl-amino)-methyl]-benzoic acid (3S,4S)-4-[2-(4-benzyl-3-hydroxy-piperidin-1-yl)-ethanesulfonyl]-phenyl ester

https://huagongshe.com/reaction/2187103

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(3S,4S)-4-[2-(4-benzyl-3-hydroxy-piperidin-1-yl)-ethanesulfonyl]-phenolHCID 9885963—
Reactant4-{[(tert-Butoxycarbonyl)(methyl)amino]methyl}benzoic acidHCID 22450242—
Product4-[(tert-Butoxycarbonyl-methyl-amino)-methyl]-benzoic acid (3S,4S)-4-[2-(4-benzyl-3-hydroxy-piperidin-1-yl)-ethanesulfonyl]-phenyl esterHCID 8658479999%

Reaction Steps

The title compound was prepared from (3S,4S)-4-[2-(4-benzyl-3-hydroxy-piperidin-1-yl)-ethanesulfonyl]-phenol and 4-[(tert-butoxycarbonyl-methyl-amino)-methyl]-benzoic acid in 99% yield as a light brown oil.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06407235B1
Source datasetuspto-grants-2002_06
ORD IDord-e5d2b87fbf7445779bf0cd94cd476409
Source noteuspto-grants-2002_06