HCID 9892240, compound → [2-(4-Methoxyphenyl)-6-methoxybenzofuran-3-yl][4-[2-diisopropylaminoethoxy]phenyl]methanol

HRID 2187111Notes

Reaction equation

HRID 2187111 reaction equation
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([C:9]2[O:10][C:11]3[CH:35]=[C:34]([O:36][CH3:37])[CH:33]=[CH:32][C:12]=3[C:13]=2[C:14]([C:16]2[CH:21]=[CH:20][C:19]([O:22][CH2:23][CH2:24][N:25]([CH:29]([CH3:31])[CH3:30])[CH:26]([CH3:28])[CH3:27])=[CH:18][CH:17]=2)=[O:15])=[CH:5][CH:4]=1>CO>[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([C:9]2[O:10][C:11]3[CH:35]=[C:34]([O:36][CH3:37])[CH:33]=[CH:32][C:12]=3[C:13]=2[CH:14]([C:16]2[CH:21]=[CH:20][C:19]([O:22][CH2:23][CH2:24][N:25]([CH:29]([CH3:31])[CH3:30])[CH:26]([CH3:27])[CH3:28])=[CH:18][CH:17]=2)[OH:15])=[CH:5][CH:4]=1

Participants

3

Reactant 1

HCID 9892240HCID 9892240, compound

Product 1

HCID 22743056[2-(4-Methoxyphenyl)-6-methoxybenzofuran-3-yl][4-[2-diisopropylaminoethoxy]phenyl]methanolYield 54.9%

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

1.5 g (3 mmol) of [2-(4-methoxyphenyl)-6-methoxybenzofuran-3-yl][4-[2-diisopropylaminoethoxy]phenyl]methanone was reduced to the carbinol by the method described in Example 1. This yielded 830 mg of the title compound as an oily solid.

Sources & evidence

ORD record
ord-f0c90167502b41659e801b436b7e412f
Source dataset
uspto-grants-2002_06
Patent number
US06407243B1

Reaction notes

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