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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 218721Generated: October 28, 2026

Methyl 4-(bromomethyl)benzoate → HCID 59597185, compound

https://huagongshe.com/reaction/218721

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl 4-(bromomethyl)benzoateHCID 256687—
Reactant5-benzyloxy-N-(6-isopropylpyridin-3-yl)-N-[(pyrazol-4-yl)methyl]-1,2,3,4-tetrahydronaphthalene-1-carboxamide hydrochlorideHCID 67183027—
ProductHCID 59597185HCID 5959718576%

Reaction Steps

By the reaction and treatment in the same manner as in Example 271 using 5-benzyloxy-N-(6-isopropylpyridin-3-yl)-N-[(pyrazol-4-yl)methyl]-1,2,3,4-tetrahydronaphthalene-1-carboxamide hydrochloride (0.66 g) and methyl 4-(bromomethyl)benzoate (0.31 g) as starting materials, methyl 4-[(4-{[N-(5-benzyloxy-1,2,3,4-tetrahydronaphthalene-1-ylcarbonyl)-N-(6-isopropylpyridin-3-yl)amino]methyl}pyrazol-1-yl)methyl]benzoate (0.61 g) was obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08198454B2
Source datasetuspto-grants-2012_06
ORD IDord-d72c50daec8c4ab0a37cc884fb8c5800
Source noteuspto-grants-2012_06