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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2187213Generated: October 28, 2026

5-Amino-2-chloropyridine → N-methyl-5-(trifluoromethyl)pyridin-3-amine

https://huagongshe.com/reaction/2187213

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-Amino-2-chloropyridineHCID 79305—
Reactant5-(Trifluoromethyl)pyridin-3-amineHCID 14051936—
ProductN-methyl-5-(trifluoromethyl)pyridin-3-amineHCID 21221268—

Reaction Steps

The reaction procedure of Reference Example 24 was repeated except that 3-amino-5-trifluoromethylpyridine was used in lieu of 5-amino-2-chloropyridine to obtain the title compound as white crystals.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06407248B1
Source datasetuspto-grants-2002_06
ORD IDord-33a3c0f1893c436385c012524d8dc5fa
Source noteuspto-grants-2002_06