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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 218723Generated: October 30, 2026

m,alpha-Dichlorotoluene → HCID 59597302, compound

https://huagongshe.com/reaction/218723

Reaction equation

Participants

RoleNameHCIDCharge
Reactantm,alpha-DichlorotolueneHCID 12103—
Reactant5-benzyloxy-N-(6-isopropylpyridin-3-yl)-N-[(pyrazol-4-yl)methyl]-1,2,3,4-tetrahydronaphthalene-1-carboxamide hydrochlorideHCID 67183027—
ProductHCID 59597302HCID 59597302—

Reaction Steps

By the reaction and treatment in the same manner as in Example 271 using 5-benzyloxy-N-(6-isopropylpyridin-3-yl)-N-[(pyrazol-4-yl)methyl]-1,2,3,4-tetrahydronaphthalene-1-carboxamide hydrochloride (0.78 g) and 3-chlorobenzyl chloride (0.38 mL) as starting materials, 5-benzyloxy-N-({1-[(3-chlorophenyl)methyl]pyrazol-4-yl}methyl)-N-(6-isopropylpyridin-3-yl)-1,2,3,4-tetrahydronaphthalene-1-carboxamide (0.77 g) was obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08198454B2
Source datasetuspto-grants-2012_06
ORD IDord-8031242de7fc4498a89a04394602333a
Source noteuspto-grants-2012_06