HuagongsheHuagongshe Chemistry Print Report · For research reference only
Tetrahydrofuran → HCID 69411554, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Tetrahydrofuran | HCID 8028 | — |
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | HCID 69410815 | HCID 69410815 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 69411554 | HCID 69411554 | 6.6% |
Reaction Steps
3β-Hydroxy-4,4-dimethylchola-5,7-dien-24-oic acid methyl ester (120 mg) is saponified in a mixture of 15 ml of methanol, 15 ml of THF and 0.7 ml of 1M sodium hydroxide at 50° C. After aqueous work-up and crystallisation from methanol, the title compound (7.6 mg) is isolated. Melting point: 210-213° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06407086B2 |
| Source dataset | uspto-grants-2002_06 |
| ORD ID | ord-bd3ad953477d472b8928ecae87a7ec7c |
| Source note | uspto-grants-2002_06 |