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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2187282Generated: October 30, 2026

Aluminium lithium hydride → HCID 69411676, compound

https://huagongshe.com/reaction/2187282

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAluminium lithium hydrideHCID 21226445—
ReactantHCID 69410951HCID 69410951—
SolventTetrahydrofuranHCID 8028—
ProductHCID 69411676HCID 6941167691.4%

Reaction Steps

3β-tert-Butyldimethylsilyloxy-4,4-dimethyl-5α-chola-8,14-dien-24-oic acid methyl ester (5.29 g) is reduced with lithium aluminium hydride (1.75 g) in 300 ml of THF at room temperature. After aqueous work-up and crystallisation from ethanol/water, 4.58 g of 3β-tert-butyldimethylsilyloxy-4,4-dimethyl-5α-chola-8,14-dien-24-ol is isolated.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06407086B2
Source datasetuspto-grants-2002_06
ORD IDord-b12ac8a548224043a47322a08ebe7bfb
Source noteuspto-grants-2002_06