Bromine → HCID 22597763, compound

HRID 2187539Notes

Reaction equation

HRID 2187539 reaction equation
[CH3:1][O:2][C:3]1[CH:11]=[C:10]([CH:12]([CH3:14])[CH3:13])[CH:9]=[CH:8][C:4]=1[C:5]([OH:7])=[O:6].[Br:15]Br>C(Cl)(Cl)Cl>[Br:15][C:9]1[C:10]([CH:12]([CH3:14])[CH3:13])=[CH:11][C:3]([O:2][CH3:1])=[C:4]([CH:8]=1)[C:5]([OH:7])=[O:6]

Participants

4

Reactant 2

HCID 24408BromineHCID 126137372-Methoxy-4-(propan-2-yl)benzoic acid

Product 1

HCID 22597763HCID 22597763, compound

Reagents, catalysts & solvents 1

HCID 6212ChloroformSolvent2×

Procedure

To a solution of 2-methoxy-4-iso-propyl benzoic acid (7.0 g, 36.0 mmol) in chloroform (100 ml) was added bromine (1.86 ml) in chloroform (20 ml) dropwise. The reaction was stirred at room temperature overnight. Evaporation in vacuo afforded an oil (9.27 g), m/z (CI); 275, 273 (MH−; 70%).

Workup

  1. customEvaporation in vacuo

Sources & evidence

ORD record
ord-681108fa6d654f00aea8e4bd5d3d2f06
Source dataset
uspto-grants-2002_06
Patent number
US06410555B1

Reaction notes

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