HuagongsheHuagongshe Chemistry Print Report · For research reference only
Piperidine → 2-[(3-Bromophenyl)methylene]propanedinitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Piperidine | HCID 8082 | — |
| Reactant | 3-Bromobenzaldehyde | HCID 76583 | — |
| Reactant | 2-Hydroxybutanedinitrile | HCID 21253562 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | 2-[(3-Bromophenyl)methylene]propanedinitrile | HCID 367526 | — |
Reaction Steps
In this situation the aldehyde, such as 3-bromobenzaldehyde as a representative example, is reacted with malonitrile in the presence of catalytic piperidine in a solvent such as dioxane to afford the 2-[(3-bromophenyl)methylene]malononitrile.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06410536B1 |
| Source dataset | uspto-grants-2002_06 |
| ORD ID | ord-b27c92dd7bb442d09ff55a98277152c8 |
| Source note | uspto-grants-2002_06 |