HCID 57123045, compound → HCID 70155699, compound

Participants

Reaction Steps

A solution of compound tert-butyl (2S)-2-{2-(4-fluorophenyl)-4-[1-(4-fluorophenyl)-2-(imidazol-1-yl)ethylamino]benzoylamino})-4-carbamoylbutyrate (example 15) (0.09 g; 0.15 mmole) in TFA (3 ml) was stirred at room temperature for 30 minutes. After evaporation to dryness, the residue was purified on reverse phase silica, eluting with methanol/ammonium carbonate buffer (2 g /1, pH 7). The appropriate fractions were concentrated and freeze-dried to give the title compound.

Provenance & Evidence