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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2187851Generated: November 3, 2026

Thionyl Chloride → HCID 18426175, compound

https://huagongshe.com/reaction/2187851

Reaction equation

Participants

RoleNameHCIDCharge
ReactantThionyl ChlorideHCID 24386—
ReactantHCID 18426279HCID 18426279—
ProductHCID 18426175HCID 18426175—

Reaction Steps

A mixture of 1-(4-carboxybenzyl)-4-[{N-(3-(trifluoromethyl)benzoyl)glycyl}aminomethyl]piperidine (240 mg) and thionyl chloride (1 mL) was stirred at room temperature for 12 h and the excess thionyl chloride was removed under reduced pressure to give desired 1-[4-(chloroformyl)benzyl]-4-[{N-(3-(trifluoromethyl)benzoyl)glycyl{aminomethyl]piperidine. The acid chloride was used without further purification.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06410566B1
Source datasetuspto-grants-2002_06
ORD IDord-4811ca488acb4a59803d215cb95a19bc
Source noteuspto-grants-2002_06