HuagongsheHuagongshe Chemistry Print Report · For research reference only
Chloroacetyl chloride → HCID 18475852, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Chloroacetyl chloride | HCID 6577 | — |
| Reactant | HCID 18475877 | HCID 18475877 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | HCID 18475852 | HCID 18475852 | — |
Reaction Steps
To a solution of the product from Step I (1 equiv) in 1:1 EtOAc-saturated NaHCO3 solution at 0° C. is added chloroacetyl chloride (3 equiv) dropwise. After completion, the layers a separated, and the organic solution is washed with water and brine, dried (Na2SO4), filtered, and concentrated in vacuo to provide the titled product.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06410534B1 |
| Source dataset | uspto-grants-2002_06 |
| ORD ID | ord-c2be024c24e342b3867f1656c01b6dff |
| Source note | uspto-grants-2002_06 |