HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-benzyloxy-N-(4-isopropylphenyl)-N-[(pyrazol-4-yl)methyl]-1,2,3,4-tetrahydronaphthalene-1-carboxamide → HCID 59597318, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-benzyloxy-N-(4-isopropylphenyl)-N-[(pyrazol-4-yl)methyl]-1,2,3,4-tetrahydronaphthalene-1-carboxamide | HCID 17854250 | — |
| Reactant | 2-(Chloromethyl)-4-methylpyridine hydrochloride | HCID 20061071 | — |
| Product | HCID 59597318 | HCID 59597318 | 70.1% |
Reaction Steps
By the reaction and treatment in the same manner as in Example 271 using 5-benzyloxy-N-(4-isopropylphenyl)-N-[(pyrazol-4-yl)methyl]-1,2,3,4-tetrahydronaphthalene-1-carboxamide (0.62 g) and 2-(chloromethyl)-4-methylpyridine hydrochloride (0.46 g) as starting materials, 5-benzyloxy-N-(4-isopropylphenyl)-N-({1-[(4-methylpyridin-2-yl)methyl]pyrazol-4-yl}methyl)-1,2,3,4-tetrahydronaphthalene-1-carboxamide (0.53 g) was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08198454B2 |
| Source dataset | uspto-grants-2012_06 |
| ORD ID | ord-4d5f0a239e594414ac36fceb7e76f1ae |
| Source note | uspto-grants-2012_06 |