Sodium Hydroxide → 4-(3,4-Dimethoxybenzoyl)benzoic acid

HRID 2187957Notes

Reaction equation

HRID 2187957 reaction equation
[CH3:1][O:2][C:3]1[CH:4]=[C:5]([CH:18]=[CH:19][C:20]=1[O:21][CH3:22])[C:6]([C:8]1[CH:17]=[CH:16][C:11]([C:12]([O:14]C)=[O:13])=[CH:10][CH:9]=1)=[O:7].[OH-].[Na+]>C(O)C>[CH3:1][O:2][C:3]1[CH:4]=[C:5]([CH:18]=[CH:19][C:20]=1[O:21][CH3:22])[C:6]([C:8]1[CH:17]=[CH:16][C:11]([C:12]([OH:14])=[O:13])=[CH:10][CH:9]=1)=[O:7]

Participants

4

Reactant 2

HCID 14798Sodium HydroxideHCID 22645197Methyl 4-(3,4-dimethoxybenzoyl)benzoate

Product 1

HCID 226452014-(3,4-Dimethoxybenzoyl)benzoic acid

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

1.3 g (4.33 mmol) of methyl 4-(3,4-dimethoxybenzoyl)benzoate was dissolved in 50 ml of ethanol. 7 ml of 1 N sodium hydroxide solution was added to the obtained solution, and they were stirred overnight. The solvent was evaporated, and the residue was washed with ethyl acetate and then filtered to obtain the title compound.

Workup

  1. customThe solvent was evaporated
  2. washthe residue was washed with ethyl acetate
  3. filtrationfiltered

Sources & evidence

ORD record
ord-098d053346434bc58ad69083a0b2469d
Source dataset
uspto-grants-2002_06
Patent number
US06410538B2

Reaction notes

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