HuagongsheHuagongshe Chemistry Print Report · For research reference only
Diisopropylamine → 2-Chloro-N,N-bis(l-methylethyl)-6-(trimethylsilyl)benzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Diisopropylamine | HCID 7912 | — |
| Reactant | 2-Chloro-6-(trimethylsilyl)benzoyl chloride | HCID 15183557 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | 2-Chloro-N,N-bis(l-methylethyl)-6-(trimethylsilyl)benzamide | HCID 18630065 | 58% |
Reaction Steps
The compound of Example b (2.47 g, 10 mmol), diisopropyl amine (2.23 g, 22 mmol), and toluene (25 mL) were combined according to General Method E2. The crude product was recrystallized from ethanol/water to afford 1.75 g of the title compound as a white solid, a 58% yield. m.p. 96-97.5° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06410558B1 |
| Source dataset | uspto-grants-2002_06 |
| ORD ID | ord-a7fdc733e951419c87779253f3a8e827 |
| Source note | uspto-grants-2002_06 |