Cyclohexanol → HCID 18477124, compound

Participants

Reaction Steps

To a mixture of 2-(N-benzylmethylamino)methyl-6-hydroxy-1-phenyl-3,4-dihydronaphthalene (0.53 g), cyclohexanol (0.26 cm3), triphenylphosphine (0.579 g) and tetrahydrofuran (20 cm3), was added diethyl azodicarboxylate (0.35 cm3) at room temperature. After stirring for 5 h the solvent was removed under reduced pressure. The crude product was purified by column chromatography [silica, eluting with ethyl acetate-heptane (1:4)] to yield the title compound (0.442 g) as a yellow oil.

Provenance & Evidence