4-Methoxybenzylamine → HCID 57139082, compound

Participants

Reaction Steps

Synthesis was performed from (2S)-2-({(2S)-2-[(tert-butoxycarbonyl)amino]-3-phenylpropanoyl}amino)-3-[3-(methoxycarbonyl)-4-(2-methoxy-2-oxoethoxy)phenyl]propanoic acid and 4-methoxybenzylamine (40 mg) according to Method B to give the title compound (33 mg). 1H-NMR (400 MHz, CD3OD) d 7.75 (s, 1H), 7.34 (dd, 1H), 7.26-7.18 (m, 5H), 7.05 (d, J=8.6 Hz, 1H), 6.94 (d, J=8.6 Hz, 2H), 6.82 (m, 2H), 4.77 (s, 2H), 4.56 (m, 1H), 4.15 (dd, J=5.1 Hz, J=14.7 Hz, 1H), 3.76 (s, 3H), 3.08-2.94 (m, 3H), 2.76 (dd, J=9.6 Hz, J=13.7 Hz, 1H), 1.33 (s, 9H); HRMS m/z 649.2615 (calc. of monoisotopic mass for C34H39N3O10 gives 649.2635).

Provenance & Evidence