HCID 21566371, compound → HCID 70161035, compound

Participants

Reaction Steps

Synthesis was performed from (2S)-2-({(2S)-2-[(tert-butoxycarbonyl)amino]-3-phenylpropanoyl}amino)-3-[3-(methoxycarbonyl)-4-(2-methoxy-2-oxoethoxy)phenyl]propanoic acid (93 mg, 0.17 mmol) and 3-phenylsalicylic acid hydrazide (45 mg, 0.20 mmol) according to Method C with HPLC purification to give the title compound (30 mg). 1H-NMR (400 MHz, CD3OD) d 4.80 (s, 2H), 4.27 (dd, J=4.9 Hz, J=9.8 Hz, 1H), 3.04 (m, 1H), 2.94 (m, 1H), 2.72 (dd, J=9.3 Hz, J=13.7 Hz, 1H), 1.34 (s, 9H); IR (KBr) 3280, 1694, 1653 cm−1; HRMS m/z 740.2666 (calc. of monoisotopic mass for C39H40N4O11 gives 740.2694).

Provenance & Evidence